Description
Project AD Liver+ — Liver Support Built Around a Full 250mg TUDCA Dose
Your liver runs somewhere north of 500 distinct jobs a day. It filters everything you swallow, converts thyroid hormone, packages fats for transport, clears metabolic byproducts from hard training, and handles every supplement in your stack before the rest of your body ever sees it. Nobody thinks about it until bloodwork says something.
Liver+ from Project AD is a six-ingredient liver support formula delivering 1,025mg of active compounds per serving in two capsules — every dose disclosed, no proprietary blend. The 2026 version builds in a full clinical dose of TUDCA, which Project AD previously sold as its own standalone bottle.
Who This Is Actually For
- You run a full stack. Pre-workout, protein, test support, vitamins — every one of those passes through hepatic metabolism. Volume of intake is volume of work.
- You train hard. High training loads raise metabolic throughput and oxidative stress, and the liver handles a meaningful share of the cleanup.
- You drink socially. Ethanol is metabolized in the liver first, generating acetaldehyde and consuming glutathione in the process.
- You're past 30. Hepatic blood flow and drug-clearance capacity both trend downward with age, on top of ordinary environmental load.
How Each Ingredient Works
TUDCA (Tauroursodeoxycholic Acid) — 250mg
TUDCA is a hydrophilic bile acid. That word matters: most bile acids are detergent-like and become cytotoxic when they pool in the liver, a state called cholestasis. TUDCA shifts the composition of the bile pool toward the less aggressive end, which is the mechanism behind its use for supporting healthy bile flow. It also acts as a chemical chaperone in the endoplasmic reticulum — helping proteins fold correctly and easing ER stress, which is a distinct pathway from the antioxidant story the rest of this formula tells. This is the ingredient that separates Liver+ from every $19 milk thistle bottle on the shelf.
Milk Thistle 4:1 Extract — 250mg
The 4:1 concentration means 250mg here is equivalent to 1,000mg of raw seed. The active fraction is silymarin, a flavonolignan complex. Its relevance isn't generic "antioxidant" hand-waving — silymarin's documented behavior includes stabilizing hepatocyte membranes and supporting the regenerative machinery of liver cells. Two thousand years of use, and still the reference point every other liver ingredient gets compared against.
N-Acetyl L-Cysteine (NAC) — 200mg
Glutathione is the body's master antioxidant, and its production is rate-limited by the availability of cysteine. NAC is the stable, bioavailable delivery form of that limiting substrate. Phase II liver detoxification depends heavily on glutathione conjugation — the step where the liver attaches glutathione to a processed compound so it can actually be excreted. Supply the substrate, support the pathway.
Artichoke Leaf Extract 10:1 — 150mg
A 10:1 concentration, equivalent to 1,500mg of raw leaf. Artichoke is choleretic — it prompts the liver to produce bile. That pairs directly with TUDCA: TUDCA improves the quality and flow of the bile pool, artichoke supports production of it. Bile is how fat gets emulsified and how a number of fat-soluble waste products physically leave the body.
Choline (as L-Bitartrate) — 100mg
Choline is required to build phosphatidylcholine, which the liver uses to assemble VLDL particles — the vehicles that transport triglycerides out of the liver and into circulation. Without adequate choline, fat that arrives at the liver has no efficient exit route and accumulates in the hepatocyte. This is the least glamorous ingredient in the formula and one of the most mechanically important.
Chinese Skullcap Root — 75mg
Scutellaria baicalensis, standardized around baicalin and related flavonoids. Its contribution is hepatoprotective antioxidant defense and support for a healthy inflammatory response — a different chemical family than silymarin, covering different ground.
Supplement Facts
| Per 2 Capsules | Amount |
|---|---|
| TUDCA Powder | 250mg |
| Milk Thistle Extract 4:1 (equiv. 1,000mg raw seed) | 250mg |
| N-Acetyl L-Cysteine (NAC) | 200mg |
| Artichoke Leaf Extract 10:1 (equiv. 1,500mg raw leaf) | 150mg |
| Choline (as Choline L-Bitartrate) | 100mg |
| Chinese Skullcap Root | 75mg |
| Total actives | 1,025mg |
60 capsules · 30 servings · no proprietary blends
Vegan · vegetarian · gluten free · dairy free · soy free · keto and paleo friendly.
How to Take Liver+
Two capsules daily with a meal and a full glass of water. Morning or evening — consistency beats timing. Liver support isn't a stimulant or a hormonal compound, so there's no cycling requirement; it's built to run continuously as a background habit.
Why We Stock It
We've sold liver support at Coalition Nutrition since 2013, and the category is full of 500mg milk thistle capsules sold at a markup. The reason Liver+ earns shelf space is the TUDCA — at 250mg, at a disclosed dose, in a formula that already covers the glutathione and bile-production angles. Buying those six compounds separately means six bottles and a handful of pills. This is two capsules.
In stock at our Langhorne storefront and shipping nationwide. If you're running a heavy stack and want a second opinion on whether this or a standalone TUDCA fits your setup better, ask us — that's the part you can't get from a marketplace listing.
Liver+ FAQ
What is TUDCA and why is it in a liver supplement?
TUDCA is a water-soluble bile acid that supports healthy bile flow and helps protect liver cells from the buildup of harsher bile acids. It also functions as a chemical chaperone that eases endoplasmic reticulum stress. It's the single most differentiated ingredient in this formula and was previously sold by Project AD as a separate product.
TUDCA or milk thistle — which one do I need?
They work on different pathways. Milk thistle's silymarin is primarily antioxidant and cell-membrane stabilizing. TUDCA acts on bile composition and cellular stress response. Liver+ includes both at 250mg each, which is why it replaces buying either one alone.
Do I need to cycle Liver+?
No. Unlike stimulant pre-workouts or hormonal support products, there's no receptor downregulation or HPTA consideration here. Liver+ is designed for continuous daily use.
Should I take Liver+ if I'm on a heavy supplement stack?
That's the exact use case it's built for. Everything you ingest is metabolized hepatically, so a larger stack means a larger daily processing load.
How many capsules per day, and how long does a bottle last?
Two capsules daily. Each bottle contains 60 capsules — a 30-day supply.
Is Liver+ vegan and allergen friendly?
Yes. Vegan, vegetarian, gluten free, dairy free and soy free, and it fits keto and paleo diets.
Who shouldn't take Liver+?
Anyone with a diagnosed liver condition should be working with a physician rather than self-managing with a supplement. Consult your healthcare provider before use if you're pregnant, nursing, under 18, or taking medication — blood thinners in particular.
Can I pick this up locally?
Yes. Liver+ is stocked at our Langhorne, PA storefront at 2026 E Old Lincoln Hwy, serving Bucks County and the greater Philadelphia area.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Liver+ is a proactive support supplement, not a treatment for liver disease. Consult your healthcare provider before use if you are pregnant, nursing, taking medication (especially blood thinners), or under 18.
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Project AD - Liver Plus
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